Mhccluster

Author: lual

August undefined, 2024

WebbThe identification of peptides binding to major histocompatibility complexes (MHC) is a critical step in the understanding of T cell immune responses. The human MHC … WebbSøgemaskine over alle forskere fra Københavns Universitet. MHCcluster, a method for functional clustering of MHC molecules. Publikation: Bidrag til tidsskrift › Tidsskriftartikel …

MHCcluster, a method for functional clustering of MHC molecules

Webb25 juli 2024 · Adverse drug reactions have been linked with HLA alleles in different studies. These HLA proteins play an essential role in the adaptive immune response for the presentation of self and non-self peptides. Anti-thyroid drugs methimazole and propylthiouracil have been associated with drug induced agranulocytosis (severe lower … WebbHLA typing of 177 human cancer and normal cell lines. Applying our pipeline to RNA-Seq data from 167 human cancer and 10 non-cancer cell lines, we generated the largest catalog of cell line HLA types (Table 1; Table S1) compiled to date.The 177 cell lines include 62 from breast tissue, including 5 non-cancerous breast cell lines and one … tema 669

MHCcluster, a method for functional clustering of MHC molecules

WebbMHCcluster, a method for functional clustering of MHC molecules Martin Thomsen, Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Building 208, Kemitorvet, … WebbMHCcluster [21]. Figure 1: Heatmaps of the MHCcluster. Figure A and B show the heatmaps for the MHC class I and II, respectively. The regions in red represent the … WebbDTU Health Tech offers access to a number of unique products and services. Based on unique facilities and specialized knowledge on a variety of health technology solutions, … tema 671

Design of a predicted MHC restricted short peptide …

Use of one-pot, mix-and-read peptide-MHC class I tetramers and …

WebbThis work describes a tool, MHCcluster, to functionally cluster MHC molecules based on their predicted binding specificity and demonstrates that conventional sequence-based … tema 682WebbThe identification of peptides binding to major histocompatibility complexes (MHC) is a critical step in the understanding of T cell immune responses. The human MHC … tema 685

"Webb17 aug. 2024 · The immunological factors that could explain the near absence of malaria parasites in bonobos are not yet understood. The MHC class I system, however, may play an important role, as particular bonobo allotypes show functional similarities to HLA-B*53/B*78, which are considered to confer protection against malaria in humans. " - Mhccluster

Mhccluster

Article abstracts - services.healthtech.dtu.dk

WebbMHCcluster, a method for functional clustering of MHC molecules - CORE ... WebbBased on predictions from NetMHCpan and MHCcluster we provide experimental evidence that redefines a CTL epi-tope on antigen Tp2 and that an epitope on antigen …

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Webb18 juni 2013 · Europe PMC is an archive of life sciences journal literature. Search life-sciences literature (41,823,436 articles, preprints and more) Webb28 apr. 2014 · Peptide-major histocompatibility complex (p-MHC) class I tetramer complexes have facilitated the early detection and functional characterisation of epitope …

WebbThese services have been discontinued for various reasons: age, porting is impossible, superseeded or no longer scientifically interesting. They will just be mentioned by name … Webb25 mars 2024 · The MHCcluster server is a tool to functionally cluster MHC class I molecules (MHC I) based on their predicted binding specificity was used . The functional relationship between the allelic variants is presented as a phylogenetic tree and/or heat-map between MHC variants [45, 81]. Secondary structure prediction

Webb17 dec. 2024 · this organism.13,14 The pathological symptoms of the disease involve a number of systemic dysfunctions including edema, hemorrhages, shock, multi organ … Webb17 sep. 2024 · In short, the MHCCluster method estimates the similarity between two MHC molecules using the correlation between predicted binding values for a large set of random natural peptides. Figure 5 shows the resulting specificity tree along with predicted binding motifs for the 14 novel DQ molecules.

WebbMHC polymorphism Funcional clustering of MHC molecules: The concept of supertypes Martin Thomsen and Morten Nielsen CBS, DTU and Instituto de Investigaciones …

WebbHere, we describe a tool, MHCcluster, to functionally cluster MHC molecules based on their predicted binding specificity. The method has a flexible web interface that allows the … tema 686WebbNew strategies are needed to develop better tools to control TB, including identification of novel antigens for vaccination. Such Mtb antigens must be expressed during Mtb infection in the major target organ, the lung, and must be capable of tema 68 tnuWebb18 juni 2013 · The MHCcluster server allows the user to select a set of MHC alleles of interest including the option of uploading a set of full-length MHC I protein sequences … tema 69120The identification of peptides binding to major histocompatibility complexes (MHC) is a critical step in the understanding of T cell immune responses. The human MHC … tema 692WebbBased on predictions from NetMHCpan and MHCcluster we provide experimental evidence that redefines a CTL epi-tope on antigen Tp2 and that an epitope on antigen Tp5 can be presented by two closely related but distinct BoLA MHC class I molecules. Material and methods Expression and purification of BoLA class I HC and β2m molecules tema 697WebbNational Center for Biotechnology Information tema 693Webb18 juni 2013 · Europe PMC is an archive of life sciences journal literature. Search life-sciences literature (Over 39 million articles, preprints and more) tema 687