Cisplatin induced hyponatremia

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August undefined, 2024

WebHyponatremia due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) or gastrointestinal loss of sodium is sometimes seen during chemotherapy. However, … WebDec 16, 2024 · Cisplatin induces acute ischemic injury, resulting in decreased renal medullary blood flow ( 24) and renal tubular cell damage ( 25 ). Meanwhile, cisplatin can block calcium ion channels to reduce COX-2 and prostaglandin, cause vasoconstriction, and eventually lead to aggravation of hypoxia ( 26 ).

Managing Severe Dysgeusia and Dysosmia in Lung Cancer …

WebApr 6, 2024 · Treatment-related grade 3/4 hyponatremia was reported in 5%–7% of MIBC patients treated with pre-operative ... NAC and prolonged survival. 34-36 It is hypothesized that these mutations may increase the sensitivity of tumor cells to cisplatin-induced DNA damage, thereby enhancing the drug's efficacy in these tumors. 37 The incidence of DDR ... WebIt is a rare side effect of cisplatin that manifests with polyuria, hypovolemia, and hyponatremia, and, because of similarities in clinical settings and laboratory values, it is … small dried flowers for crafts

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WebAug 1, 2002 · We report a case of a patient with hyponatremia and excessive urinary excretion of sodium after cisplatin-based chemotherapy. RSWS was diagnosed and the … WebThe syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is a condition characterized by hypotonic and euvolemic hyponatremia along with urinary hyperosmolarity, resulting from antidiuretic hormone (ADH) release in the absence of adequate stimuli. This term was first used in 1957, when Schwartz et al described … WebApr 12, 2024 · At the same time, hyponatremia should be related to brain and adrenal metastasis, paraneoplastic syndrome, ... In this case, the standard approach to avoid cisplatin-induced nephrotoxicity and the consequent electrolyte alteration is the administration of IV isotonic saline solution in order to stimulate the diuresis. Some … small dried flowers

A Review of Drug-Induced Hyponatremia - ajkd.org

Differential diagnosis of hyponatremia induced by …

WebHyponatremia (Surgery-induced Hyponatremia Model) Leukopenia (Cyclophosphamide-induced Leukopenia Model) Hepatic and Biliary Disorders. ... Cisplatin Induced Hearing Loss Model ; Noise Induced Hearing Loss Model; In Vitro Research Model . Cochlea Explant Culture ; Ototoxicity Evaluation. WebNational Center for Biotechnology Information small dried fishWebNov 1, 1997 · Cisplatin regimens can lead to a more or less pronounced hyponatremia in 4 to 10% of cases due to salt wasting with hypomagnesemia and normokaliemia. … small driftwood for aquarium

"WebWe report a rare case of severe hyponatremia due to cisplatin-induced syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in a 74-year-old male with a … " - Cisplatin induced hyponatremia

Cisplatin induced hyponatremia

Cisplatin-induced acute hyponatremia leading to a seizure and …

WebThe possibility of Cisplatin induced renal salt wasting was considered. The patient was started on Fludrocortisone 0.1mg twice daily, oral salt tablets 1g QID, sodium bicarbonate tablets 650mg TID and normal saline at 150ml/h. ... PROFOUND HYPONATREMIA AND DEHYDRATION: A CASE OF CISPLATIN INDUCED SALT LOSING NEPHROPATHY. … WebFeb 1, 1995 · Cisplatin, pharmacology and clinical applications Article Feb 2012 S. Ithimakin View Show abstract A Case of Severe Hyponatremia Caused by Renal Salt Wasting Syndrome in Oropharyngeal Cancer...

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WebAbstract We report a rare case of cisplatin-induced acute hyponatremia leading to a seizure and coma. A 66-year-old woman with breast cancer received adjuvant chemotherapy with docetaxel and cisplatin. She had no nausea, vomiting, or diarrhea during or after chemotherapy administration. WebJan 13, 2024 · In addition, significant hyponatremia signals were detected for oesophageal, lung, and renal cancers. Conclusions: Hyponatremia has been reported in women and patients with lung cancer...

WebJul 8, 2010 · Cisplatin based therapy for the treatment of solid organ tumors is commonly associated with several renal abnormalities including; *hypokalemia. * hypomagnesemia. … WebMar 1, 2024 · A case of an elderly male presenting with significant recurrent hyponatremia, and prerenal azotemia, with recent exposure to cisplatin along with significant hypovolemia and urinary loss of sodium is reported. Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude …

WebFluid restriction is the hallmark of SIADH treatment, while increased sodium intake remains the hallmark of RSWS treatment. 6 This patient presented with a combination of cisplatin-induced acute kidney injury (AKI) and … WebFeb 1, 2016 · The marked urinary losses of sodium in combination with a negative sodium balance led to the diagnosis of cisplatin-induced renal salt wasting syndrome (RSWS). The subsequent clinical...

WebDec 21, 2024 · Inamori M, Inohara H, Horii A. Diﬀerential diagnosis of hyponatremia induced by cisplatin-con taining chemotherapy: syndrome of inappropriate secretion of an tidiuretic hormone (SIADH) or renal ...

Webwasting due to cisplatin therapy. Although patients with cancer have hyponatremia due to many etiologies (Table 1), SIADH is the most common etiol- ... hyponatremia via potentiation of ADH release or action, in-cluding vinblastine, vincristine, and cyclophosphamide (7). ... or steroid-induced ulcer disease) Decreased effective … small drill press lowe\u0027sWebCDDP-induced hyponatremia has also occurred in a case of renal salt-wasting syndrome, 4 in patients with nausea/vomiting/anorexia, and when vigorous hydration was … small driftwood style dining tableWebIntroductionLung cancer (LC) is highly prevalent worldwide, with elevated mortality. In this population, taste and smell alterations (TSAs) are frequent but overlooked symptoms. The absence of effective therapeutic strategies and evidence-based songbird by fleetwood mac karaokeWebAug 1, 2002 · We report a case of a patient with hyponatremia and excessive urinary excretion of sodium after cisplatin-based chemotherapy. RSWS was diagnosed and the patient was treated with a sodium supplement. We also summarize the key diagnostic features and the most common differential diagnoses for hyponatremia syndrome. small drill chuck harbor freightWebCisplatin is a well-known chemotherapeutic agent that can be associated with hyponatremia. Mechanisms of cisplatin-induced hyponatremia include renal salt wasting syndrome … songbird by fleetwood mac lyricsWebBoth renal salt-wasting syndrome (RSWS) and syndrome of inappropriate antidiuretic hormone secretion (SIADH) have been reported as the underlying mechanisms for chemotherapy-induced hyponatremia. However, these two clinical syndromes have distinct clinical characteristics and managements. small drill bit chuckWebMar 1, 2024 · Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude of renal disorders including … small drill bit sizes chart